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Is varenicline safe in pregnancy? Available medications include nicotine replacement therapy, sustained-release bupropion, and varenicline. Nicotine replacement therapy and bupropion do not appear to increase the risk of major malformations; however, there is currently limited evidence on the use of varenicline during pregnancy. How long does one drag of a cigarette stay in your system? Generally, nicotine leaves your blood 1-3 days after you stop using tobacco, and cotinine (something your body makes after nicotine enters it) will be gone after 1-10 days. Neither will show up in your urine after 3-4 days. Does Chantix have permanent side effects? These reports added to concerns about two stop-smoking drugs, Chantix and Zyban. Nicotine withdrawal can also cause mental health problems similar to those caused by Chantix and Zyban, such as depression, anxiety, irritability, restlessness, and sleep disturbance. Does smoking affect radiation treatment? Smoking During Breast Cancer Radiation Therapy Increases Risk of Lung Cancer. A study reinforces the results of earlier research: Besides causing many diseases and increasing breast cancer risk, smoking can increase complications from radiation therapy.
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